Pharmaceutical Preparations
Lyell Immunopharma, Inc., a clinical-stage cell therapy company, engages in developing T-cell reprogramming technologies for patients with solid tumors. It develops therapies using an ex vivo genetic reprogramming technologies, such as c-Jun overexpression and NR4A3 gene knockout, to endow resistance to T-cell exhaustion; and an ex vivo epigenetic reprogramming technologies, including Epi-R to generate population of T cells with durable stemness, and Stim-R, a proprietary synthetic cell mimetic. The company's pipeline includes LYL797, a genetically and epigenetically reprogrammed ROR1 chimeric antigen receptor (CAR) T-cell product candidate for the treatment of various solid tumors; LYL845, an epigenetically reprogrammed tumor-infiltrating lymphocytes product candidate that targets multiple solid tumors; LYL119, a CAR T-cell product candidate for enhanced cytotoxicity. The company was incorporated in 2018 and is headquartered in South San Francisco, California.
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In the chart Earnings are multiplied by this value.
High margins render the company resilient under dire circumstances, hence able to drive competitors out or acquire them. ROE and ROA measure the average flow generated by each invested dollar. Their marginal value is a forecast of future growth, and it is considered by Buffett and Munger the most important single indicator.
Years | 12-2019 | 12-2020 | 12-2021 | 12-2022 | 12-2023 | TTM |
---|---|---|---|---|---|---|
Net Margin | -20K% | -2.7K% | -2.3K% | -220% | -180K% | -340K% |
ROA | - | -23% | -19% | -20% | -33% | -35% |
ROE | 120% | 71% | -27% | -22% | -36% | -38% |
The average Net Margin over the past 5 years is -180.49K%.
The trend of Net Margin over the past 5 years is -.
The average ROA over the past 5 years is -32.93%.
The trend of ROA over the past 5 years is -.
The average ROE over the past 5 years is -35.82%.
The trend of ROE over the past 5 years is -.
Being debt the number one cause of investment losses and company death, the ratio Debt/FCF is of utmost importance to guarantee safety. On the other hand the Graham’s stability measures the drawdown of earnings, hence indicating the reliability of the flow generated by the company.
Years | 12-2019 | 12-2020 | 12-2021 | 12-2022 | 12-2023 | TTM | ||||
---|---|---|---|---|---|---|---|---|---|---|
Debt FCF | - | - | - | - | - | - | ||||
Debt Equity | - | - | - | - | - | - | ||||
MIN | ||||||||||
Graham Stability | - | - | - | - | - | - |
The Debt/FCF trailing twelve month is -.
The trend of Debt/FCF over the past 5 years is -.
Graham’s Stability measure stands at -.
Growth can be dangerous when forecasting, simply projecting the current growth is in general wrong. A company passes through multiple phases, from being young and unprofitable, to the first periods of profitability and high growth, until it arrives at a period of regime with limited growth. Identifying in which phase the company is in may help forecasting.
Years | 12-2020 | 12-2022 | Trend |
---|---|---|---|
Revenue | -74% | -100% | -290% |
Net Income | - | - | - |
Stockholders Equity | - | -21% | -11% |
FCF | - | - | - |
The Revenue CAGR over the past 5 years is -.
The trend of Revenue growth rate over the past 5 years is -288.33%.
The Earnings CAGR over the past 5 years is -.
The trend of Earnings growth rate over the past 5 years is -.
The Equity CAGR over the past 5 years is -.
The trend of Equity growth rate over the past 5 years is -11.02%.
The FCF CAGR over the past 5 years is -.
The trend of FCF growth rate over the past 5 years is -.