Ionis Pharmaceuticals Inc

  • Earnings Score
  • Moat Score
  • Market Cap $5.10B
  • PE -11
  • Debt -
  • Cash $264.19M
  • EV -
  • FCF -$555.15M

Earnings

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Sales & Net Margins

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Earnings-$458.03M
EBIT-$464.16M
ROE-96%
ROA-17%
FCF-$555.15M
Equity$475.73M
Growth Stability-384%
PE-11.13
PB10.72
P/FCF-9.19
P/S7.11
Price/Cash0.05
Net Margins-112%
Gross Margins99%
Op. Margins-65%
Earnings CAGR-0%
Sales Growth YoY10%
Sales Growth QoQ-42%
Sales CAGR10%
FCF CAGR-2%
Equity CAGR9%
Earnings Stability0
Earnings Growth YoY3%
Earnings Growth QoQ41%
Sales CAGR 5Y-3%
FCF CAGR 5Y1%
Equity CAGR 5Y-20%
Earnings CAGR 3Y1%
Sales CAGR 3Y1%
Equity CAGR 3Y-8%
Market Cap$5.10B
Revenue$717.25M
Assets$2.81B
Cash$264.19M
Shares Outstanding158.74M
Earnings Score6%
Moat Score1%
Working Capital2.17B
Current Ratio9.66
Gross Profit$706.73M
Shares Growth 3y3%
Equity Growth QoQ-19%
Equity Growth YoY60%

Assets & ROA

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Stockholders Equity & ROE

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Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and partner Biogen brought Spinraza to market in 2016 as a treatment for a rare neuromuscular disorder, spinal muscular atrophy. Ionis subsequently brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019).

SEC Filings

Direct access to Ionis Pharmaceuticals Inc (IONS) Annual Reports (10K) and Quarterly Reports (10Q) from the SEC website.

  • 2025
    • 10-Q Mar 31
  • 2024
    • 10-K Dec 31
    • 10-Q Sep 30
    • 10-Q Jun 30
    • 10-Q Mar 31
  • 2023
    • 10-K Dec 31
    • 10-Q Sep 30
    • 10-Q Jun 30
    • 10-Q Mar 31

Sector Comparison

How does Ionis Pharmaceuticals Inc compare to its competitors?

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Peter Lynch's Chart

This chart shows the current pricing of Ionis Pharmaceuticals Inc compared to its past. The addition of the earnings trend line provides further insights into the company's earnings power.

CAGR -0%
Stability 0%
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Ionis Pharmaceuticals Inc Discounted Cash Flow

Fully customizable DCF calculator online for Ionis Pharmaceuticals Inc.

= -$5B
012345678910TV
fcf-$555M-$546M-$537M-$528M-$519M-$510M-$501M-$493M-$485M-$476M-$468M-$4.7B
DCF-$496M-$443M-$396M-$354M-$317M-$283M-$253M-$226M-$202M-$181M-$1.8B
Value-$5B

Competitiveness and MOAT

High margins render the company resilient under dire circumstances, hence able to drive competitors out or acquire them. ROE and ROA measure the average flow generated by each invested dollar. Their marginal value is a forecast of future growth, and it is considered by Buffett and Munger the most important single indicator.

Years05/201512/201512/201612/201712/201812/201912/202012/202112/202212/202312/2024TTM
Net Margins--31%-25%-3%36%26%-67%-4%-46%-47%-64%-112%
ROA---5%2%-1%12%-5%-1%-10%-11%-15%-17%
ROE---87%-4%18%17%-58%-4%-47%-95%-77%-96%

Safety and Stability

Being debt the number one cause of investment losses and company death, the ratio Debt/FCF is of utmost importance to guarantee safety. On the other hand the Graham’s stability measures the drawdown of earnings, hence indicating the reliability of the flow generated by the company.

Years05/201512/201512/201612/201712/201812/201912/202012/202112/202212/202312/2024TTM
Debt over FCF---4.213.840.992.51.09K0-4.12-4.08-2.29-
Debt over Equity-05.041.280.490.47102.083.52.13-
Growth Stability-----100%-297%-384%----384%

Growth

Growth can be dangerous when forecasting, simply projecting the current growth is in general wrong. A company passes through multiple phases, from being young and unprofitable, to the first periods of profitability and high growth, until it arrives at a period of regime with limited growth. Identifying in which phase the company is in may help forecasting.

Years05/201512/201512/201612/201712/201812/201912/202012/202112/202212/202312/2024CAGR 5Y
Revenue YoY growth-211%22%46%18%87%-35%11%-28%34%-10%-3%
Earnings YoY growth---2%-80%-1K%37%-265%-94%843%36%24%-
Equity YoY growth---50%321%184%42%-50%-8%-26%-33%52%-20%
FCF YoY growth---987%-217%323%-47%-100%2K%-2K%14%65%1%